6R92
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | I | Human alpha-satellite DNA (145-MER) | polymer | 145 | 44756.6 | 1 | Homo sapiens | ||
| 2 | J | Human alpha-satellite DNA (145-MER) with abasic sites at positions 93-94 | polymer | 145 | 44452.4 | 1 | Homo sapiens | ||
| 3 | L | DNA damage-binding protein 2 | polymer | 450 | 50601.8 | 1 | UniProt (Q92466) Pfam (PF00400) In PDB | Homo sapiens (Human) | DDB p48 subunit,DDBb,Damage-specific DNA-binding protein 2,UV-damaged DNA-binding protein 2,UV-DDB 2 |
| 4 | A, E | Histone H3.1 | polymer | 139 | 15719.4 | 2 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 5 | B, F | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
| 6 | C, G | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 7 | D, H | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 8 | K | DNA damage-binding protein 1,DNA damage-binding protein 1 | polymer | 1163 | 129766.3 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (Human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe,DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
Sequence modifications
L: 1 - 427 (UniProt: Q92466)
A, E: 1 - 136 (UniProt: P68431)
B, F: 1 - 103 (UniProt: P62805)
C, G: 1 - 130 (UniProt: P04908)
D, H: 1 - 126 (UniProt: P06899)
K: 1 - 395 (UniProt: Q16531)
K: 706 - 1140 (UniProt: Q16531)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Ala -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Trp -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Phe -14 | - | expression tag |
| Glu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Asn -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Ala -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Trp -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Phe -14 | - | expression tag |
| Glu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Asn -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ile 396 | - | linker |
| His 397 | - | linker |
| Glu 398 | - | linker |
| His 399 | - | linker |
| Ala 400 | - | linker |
| Ser 401 | - | linker |
| Ile 402 | - | linker |
| Asp 403 | - | linker |
| Leu 404 | - | linker |
| Pro 405 | - | linker |
| Gly 406 | - | linker |
| Ile 407 | - | linker |
| Lys 408 | - | linker |
| Gly 409 | - | linker |
| Leu 410 | - | linker |
| Trp 411 | - | linker |
| Pro 412 | - | linker |
| Leu 413 | - | linker |
| Arg 414 | - | linker |
| Ser 415 | - | linker |
| Asp 416 | - | linker |
| Pro 417 | - | linker |
| Asn 418 | - | linker |
| Arg 419 | - | linker |
| Glu 420 | - | linker |
| Thr 421 | - | linker |
| Asp 422 | - | linker |
| Asp 423 | - | linker |
| Thr 424 | - | linker |
| Leu 425 | - | linker |
| Val 426 | - | linker |
| Leu 427 | - | linker |
| Ser 428 | - | linker |
| Phe 429 | - | linker |
| Val 430 | - | linker |
| Gly 431 | - | linker |
| Gln 432 | - | linker |
| Thr 433 | - | linker |
| Arg 434 | - | linker |
| Val 435 | - | linker |
| Leu 436 | - | linker |
| Met 437 | - | linker |
| Leu 438 | - | linker |
| Asn 439 | - | linker |
| Gly 440 | - | linker |
| Glu 441 | - | linker |
| Glu 442 | - | linker |
| Val 443 | - | linker |
| Glu 444 | - | linker |
| Glu 445 | - | linker |
| Thr 446 | - | linker |
| Glu 447 | - | linker |
| Leu 448 | - | linker |
| Met 449 | - | linker |
| Gly 450 | - | linker |
| Phe 451 | - | linker |
| Val 452 | - | linker |
| Asp 453 | - | linker |
| Asp 454 | - | linker |
| Gln 455 | - | linker |
| Gln 456 | - | linker |
| Thr 457 | - | linker |
| Phe 458 | - | linker |
| Phe 459 | - | linker |
| Cys 460 | - | linker |
| Gly 461 | - | linker |
| Asn 462 | - | linker |
| Val 463 | - | linker |
| Ala 464 | - | linker |
| His 465 | - | linker |
| Gln 466 | - | linker |
| Gln 467 | - | linker |
| Leu 468 | - | linker |
| Ile 469 | - | linker |
| Gln 470 | - | linker |
| Ile 471 | - | linker |
| Thr 472 | - | linker |
| Ser 473 | - | linker |
| Ala 474 | - | linker |
| Ser 475 | - | linker |
| Val 476 | - | linker |
| Arg 477 | - | linker |
| Leu 478 | - | linker |
| Val 479 | - | linker |
| Ser 480 | - | linker |
| Gln 481 | - | linker |
| Glu 482 | - | linker |
| Pro 483 | - | linker |
| Lys 484 | - | linker |
| Ala 485 | - | linker |
| Leu 486 | - | linker |
| Val 487 | - | linker |
| Ser 488 | - | linker |
| Glu 489 | - | linker |
| Trp 490 | - | linker |
| Lys 491 | - | linker |
| Glu 492 | - | linker |
| Pro 493 | - | linker |
| Gln 494 | - | linker |
| Ala 495 | - | linker |
| Lys 496 | - | linker |
| Asn 497 | - | linker |
| Ile 498 | - | linker |
| Ser 499 | - | linker |
| Val 500 | - | linker |
| Ala 501 | - | linker |
| Ser 502 | - | linker |
| Cys 503 | - | linker |
| Asn 504 | - | linker |
| Ser 505 | - | linker |
| Ser 506 | - | linker |
| Gln 507 | - | linker |
| Val 508 | - | linker |
| Val 509 | - | linker |
| Val 510 | - | linker |
| Ala 511 | - | linker |
| Val 512 | - | linker |
| Gly 513 | - | linker |
| Arg 514 | - | linker |
| Ala 515 | - | linker |
| Leu 516 | - | linker |
| Tyr 517 | - | linker |
| Tyr 518 | - | linker |
| Leu 519 | - | linker |
| Gln 520 | - | linker |
| Ile 521 | - | linker |
| His 522 | - | linker |
| Pro 523 | - | linker |
| Gln 524 | - | linker |
| Glu 525 | - | linker |
| Leu 526 | - | linker |
| Arg 527 | - | linker |
| Gln 528 | - | linker |
| Ile 529 | - | linker |
| Ser 530 | - | linker |
| His 531 | - | linker |
| Thr 532 | - | linker |
| Glu 533 | - | linker |
| Met 534 | - | linker |
| Glu 535 | - | linker |
| His 536 | - | linker |
| Glu 537 | - | linker |
| Val 538 | - | linker |
| Ala 539 | - | linker |
| Cys 540 | - | linker |
| Leu 541 | - | linker |
| Asp 542 | - | linker |
| Ile 543 | - | linker |
| Thr 544 | - | linker |
| Pro 545 | - | linker |
| Leu 546 | - | linker |
| Gly 547 | - | linker |
| Asp 548 | - | linker |
| Ser 549 | - | linker |
| Asn 550 | - | linker |
| Gly 551 | - | linker |
| Leu 552 | - | linker |
| Ser 553 | - | linker |
| Pro 554 | - | linker |
| Leu 555 | - | linker |
| Cys 556 | - | linker |
| Ala 557 | - | linker |
| Ile 558 | - | linker |
| Gly 559 | - | linker |
| Leu 560 | - | linker |
| Trp 561 | - | linker |
| Thr 562 | - | linker |
| Asp 563 | - | linker |
| Ile 564 | - | linker |
| Ser 565 | - | linker |
| Ala 566 | - | linker |
| Arg 567 | - | linker |
| Ile 568 | - | linker |
| Leu 569 | - | linker |
| Lys 570 | - | linker |
| Leu 571 | - | linker |
| Pro 572 | - | linker |
| Ser 573 | - | linker |
| Phe 574 | - | linker |
| Glu 575 | - | linker |
| Leu 576 | - | linker |
| Leu 577 | - | linker |
| His 578 | - | linker |
| Lys 579 | - | linker |
| Glu 580 | - | linker |
| Met 581 | - | linker |
| Leu 582 | - | linker |
| Gly 583 | - | linker |
| Gly 584 | - | linker |
| Glu 585 | - | linker |
| Ile 586 | - | linker |
| Ile 587 | - | linker |
| Pro 588 | - | linker |
| Arg 589 | - | linker |
| Ser 590 | - | linker |
| Ile 591 | - | linker |
| Leu 592 | - | linker |
| Met 593 | - | linker |
| Thr 594 | - | linker |
| Thr 595 | - | linker |
| Phe 596 | - | linker |
| Glu 597 | - | linker |
| Ser 598 | - | linker |
| Ser 599 | - | linker |
| His 600 | - | linker |
| Tyr 601 | - | linker |
| Leu 602 | - | linker |
| Leu 603 | - | linker |
| Cys 604 | - | linker |
| Ala 605 | - | linker |
| Leu 606 | - | linker |
| Gly 607 | - | linker |
| Asp 608 | - | linker |
| Gly 609 | - | linker |
| Ala 610 | - | linker |
| Leu 611 | - | linker |
| Phe 612 | - | linker |
| Tyr 613 | - | linker |
| Phe 614 | - | linker |
| Gly 615 | - | linker |
| Leu 616 | - | linker |
| Asn 617 | - | linker |
| Ile 618 | - | linker |
| Glu 619 | - | linker |
| Thr 620 | - | linker |
| Gly 621 | - | linker |
| Leu 622 | - | linker |
| Leu 623 | - | linker |
| Ser 624 | - | linker |
| Asp 625 | - | linker |
| Arg 626 | - | linker |
| Lys 627 | - | linker |
| Lys 628 | - | linker |
| Val 629 | - | linker |
| Thr 630 | - | linker |
| Leu 631 | - | linker |
| Gly 632 | - | linker |
| Thr 633 | - | linker |
| Gln 634 | - | linker |
| Pro 635 | - | linker |
| Thr 636 | - | linker |
| Val 637 | - | linker |
| Leu 638 | - | linker |
| Arg 639 | - | linker |
| Thr 640 | - | linker |
| Phe 641 | - | linker |
| Arg 642 | - | linker |
| Ser 643 | - | linker |
| Leu 644 | - | linker |
| Ser 645 | - | linker |
| Thr 646 | - | linker |
| Thr 647 | - | linker |
| Asn 648 | - | linker |
| Val 649 | - | linker |
| Phe 650 | - | linker |
| Ala 651 | - | linker |
| Cys 652 | - | linker |
| Ser 653 | - | linker |
| Asp 654 | - | linker |
| Arg 655 | - | linker |
| Pro 656 | - | linker |
| Thr 657 | - | linker |
| Val 658 | - | linker |
| Ile 659 | - | linker |
| Tyr 660 | - | linker |
| Ser 661 | - | linker |
| Ser 662 | - | linker |
| Asn 663 | - | linker |
| His 664 | - | linker |
| Lys 665 | - | linker |
| Leu 666 | - | linker |
| Val 667 | - | linker |
| Phe 668 | - | linker |
| Ser 669 | - | linker |
| Asn 670 | - | linker |
| Val 671 | - | linker |
| Asn 672 | - | linker |
| Leu 673 | - | linker |
| Lys 674 | - | linker |
| Glu 675 | - | linker |
| Val 676 | - | linker |
| Asn 677 | - | linker |
| Tyr 678 | - | linker |
| Met 679 | - | linker |
| Cys 680 | - | linker |
| Pro 681 | - | linker |
| Leu 682 | - | linker |
| Asn 683 | - | linker |
| Ser 684 | - | linker |
| Asp 685 | - | linker |
| Gly 686 | - | linker |
| Tyr 687 | - | linker |
| Pro 688 | - | linker |
| Asp 689 | - | linker |
| Ser 690 | - | linker |
| Leu 691 | - | linker |
| Ala 692 | - | linker |
| Leu 693 | - | linker |
| Ala 694 | - | linker |
| Asn 695 | - | linker |
| Asn 696 | - | linker |
| Ser 697 | - | linker |
| Thr 698 | - | linker |
| Leu 699 | - | linker |
| Thr 700 | - | linker |
| Ile 701 | - | linker |
| Gly 702 | - | linker |
| Thr 703 | - | linker |
| Ile 704 | - | linker |
| Asp 705 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 381700.2 | |
| All* | Total formula weight | 381700.2 |
