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6GVW

Crystal structure of the BRCA1-A complex

Summary for 6GVW
Entry DOI10.2210/pdb6gvw/pdb
Related6H3C
DescriptorBRCA1-A complex subunit Abraxas 1, Lys-63-specific deubiquitinase BRCC36, BRISC and BRCA1-A complex member 2, ... (7 entities in total)
Functional Keywordsdeubiquitinase complex, dub, lysine-63 linkage specific, brcc36-containing, brca1a binding, signaling protein
Biological sourceMus musculus (House mouse)
More
Total number of polymer chains10
Total formula weight337213.98
Authors
Bunker, R.D.,Rabl, J.,Thoma, N.H. (deposition date: 2018-06-21, release date: 2019-07-10, Last modification date: 2019-08-21)
Primary citationRabl, J.,Bunker, R.D.,Schenk, A.D.,Cavadini, S.,Gill, M.E.,Abdulrahman, W.,Andres-Pons, A.,Luijsterburg, M.S.,Ibrahim, A.F.M.,Branigan, E.,Aguirre, J.D.,Marceau, A.H.,Guerillon, C.,Bouwmeester, T.,Hassiepen, U.,Peters, A.H.F.M.,Renatus, M.,Gelman, L.,Rubin, S.M.,Mailand, N.,van Attikum, H.,Hay, R.T.,Thoma, N.H.
Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75:483-497.e9, 2019
Cited by
PubMed: 31253574
DOI: 10.1016/j.molcel.2019.06.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.75 Å)
Structure validation

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