6GVW
Crystal structure of the BRCA1-A complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | BRCA1-A complex subunit Abraxas 1 | polymer | 411 | 46431.4 | 2 | UniProt (Q8BPZ8) Pfam (PF21125) | Mus musculus (House mouse) | Coiled-coil domain-containing protein 98,Protein FAM175A |
| 2 | B, G (B, G) | Lys-63-specific deubiquitinase BRCC36 | polymer | 295 | 33711.4 | 2 | UniProt (P46737) Pfam (PF01398) Pfam (PF18110) | Mus musculus (House mouse) | BRCA1-A complex subunit BRCC36,BRCA1/BRCA2-containing complex subunit 3,BRCA1/BRCA2-containing complex subunit 36,BRISC complex subunit BRCC36 |
| 3 | C, H (C, H) | BRISC and BRCA1-A complex member 2 | polymer | 387 | 43915.8 | 2 | UniProt (Q8K3W0) Pfam (PF06113) | Mus musculus (House mouse) | BRCA1-A complex subunit BRE,BRCA1/BRCA2-containing complex subunit 45,Brain and reproductive organ-expressed protein |
| 4 | D, I (D, I) | BRISC and BRCA1-A complex member 1 | polymer | 337 | 37155.4 | 2 | UniProt (Q3UI43) | Mus musculus (House mouse) | Mediator of RAP80 interactions and targeting subunit of 40 kDa,New component of the BRCA1-A complex |
| 5 | E, J (E, J) | BRCA1-A complex subunit RAP80 | polymer | 64 | 7327.5 | 2 | UniProt (Q5U5Q9) | Mus musculus (House mouse) | Receptor-associated protein 80,Ubiquitin interaction motif-containing protein 1 |
| 6 | K, L (B, G) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | M, N (B, G) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 407 (UniProt: Q8BPZ8)
B, G: 1 - 291 (UniProt: P46737)
C, H: 1 - 383 (UniProt: Q8K3W0)
D, I: 1 - 333 (UniProt: Q3UI43)
E, J: 275 - 334 (UniProt: Q5U5Q9)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 271 | - | expression tag |
| Gly 272 | - | expression tag |
| Gly 273 | - | expression tag |
| Arg 274 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 337083.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 337214.0 |
