1MJE

STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX

Summary for 1MJE

• Entry DOI: 10.2210/pdb1mje/pdb
• Related: 1IYJ
• Descriptor: 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2 (3 entities in total)
• Functional Keywords: tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein-dna complex, gene regulation/antitumor protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 83047.98

Authors

Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. (deposition date: 2002-08-27, release date: 2002-09-27, Last modification date: 2024-02-14)

• Primary citation: Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P.; BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.; Science, 297:1837-1848, 2002; PubMed: 12228710; DOI: 10.1126/science.297.5588.1837

Experimental method

X-RAY DIFFRACTION (3.5 Å)