1IYJ
STRUCTURE OF A BRCA2-DSS1 COMPLEX
Summary for 1IYJ
Entry DOI | 10.2210/pdb1iyj/pdb |
Related | 1MIU 1MJE |
Descriptor | Deleted in split hand/split foot protein 1, breast cancer susceptibility (2 entities in total) |
Functional Keywords | tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein complex, gene regulation/antitumor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 200018.88 |
Authors | Pavletich, N.P.,Jeffrey, P.D.,Yang, H.J. (deposition date: 2002-08-28, release date: 2002-10-02, Last modification date: 2023-12-27) |
Primary citation | Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science, 297:1837-1848, 2002 Cited by PubMed: 12228710DOI: 10.1126/science.297.5588.1837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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