6R8Y

Cryo-EM structure of NCP-6-4PP(-1)-UV-DDB

Summary for 6R8Y

EMDB information4762
DescriptorHistone H3.1, Histone H4, Histone H2A type 1-B/E, ... (9 entities in total)
Functional Keywordsdna damage, nucleosome, 6-4 photoproduct, dna binding protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains12
Total molecular weight377018.11
Authors
Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Thoma, N.H. (deposition date: 2019-04-02, release date: 2019-06-12, Last modification date: 2019-07-17)
Primary citation
Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Grand, R.S.,Potenza, A.,Rabl, J.,Yamamoto, J.,Schenk, A.D.,Schubeler, D.,Iwai, S.,Sugasawa, K.,Kurumizaka, H.,Thoma, N.H.
DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571:79-84, 2019
PubMed: 31142837 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-019-1259-3
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers3 0.3% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures