6R8Y
Cryo-EM structure of NCP-6-4PP(-1)-UV-DDB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.1 | polymer | 139 | 15719.4 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B (B) | Histone H4 | polymer | 106 | 11676.7 | 1 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 3 | C, G (C, G) | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 4 | D, H (D, H) | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 5 | F (F) | Histone H4 | polymer | 103 | 11394.4 | 1 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 6 | I (I) | Human alpha-satellite DNA (145-MER) | polymer | 145 | 44780.7 | 1 | Homo sapiens | ||
| 7 | J (J) | Human alpha-satellite DNA (145-MER) with a 6-4PP at positions 95-96 | polymer | 144 | 44709.6 | 1 | Homo sapiens | ||
| 8 | K (K) | DNA damage-binding protein 1 | polymer | 1144 | 127425.8 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (Human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 9 | L (L) | DNA damage-binding protein 2 | polymer | 431 | 48261.3 | 1 | UniProt (Q92466) Pfam (PF00400) | Homo sapiens (Human) | DDB p48 subunit,DDBb,Damage-specific DNA-binding protein 2,UV-damaged DNA-binding protein 2,UV-DDB 2 |
Sequence modifications
A, E: 1 - 136 (UniProt: P68431)
B: 1 - 103 (UniProt: P62805)
C, G: 1 - 130 (UniProt: P04908)
D, H: 1 - 126 (UniProt: P06899)
K: 1 - 1140 (UniProt: Q16531)
L: 1 - 427 (UniProt: Q92466)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 377018.1 | |
| All* | Total formula weight | 377018.1 |
