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5IR6
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BU of 5ir6 by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
分子名称: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
著者Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
登録日2016-03-12
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
5DOQ
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BU of 5doq by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
分子名称: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
著者Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
登録日2015-09-11
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
7KXS
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BU of 7kxs by Molmil
Computational design of constitutively active cGAS
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P.
登録日2020-12-04
公開日2021-12-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Computational design of constitutively active cGAS.
Nat.Struct.Mol.Biol., 30, 2023
7LZ3
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BU of 7lz3 by Molmil
Computational design of constitutively active cGAS
分子名称: Cyclic GMP-AMP synthase, GLYCEROL, ZINC ION
著者Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P.
登録日2021-03-08
公開日2022-03-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Computational design of constitutively active cGAS.
Nat.Struct.Mol.Biol., 30, 2023
6D0T
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BU of 6d0t by Molmil
De novo design of a fluorescence-activating beta barrel - BB1
分子名称: BB1
著者Dou, J, Vorobieva, A.A, Sheffler, W, Doyle, L.A, Park, H, Bick, M.J, Mao, B, Foight, G.W, Lee, M, Carter, L, Sankaran, B, Ovchinnikov, S, Marcos, E, Huang, P, Vaughan, J.C, Stoddard, B.L, Baker, D.
登録日2018-04-10
公開日2018-09-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
9BEI
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BU of 9bei by Molmil
Cryo-EM structure of synthetic claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-2, and Nanobody
分子名称: Anti-fab nanobody, COP-2 Fab Heavy chain, COP-2 Fab Light chain, ...
著者Vecchio, A.J.
登録日2024-04-15
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins
To be published
8DT0
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BU of 8dt0 by Molmil
Scaffolding protein functional sites using deep learning
分子名称: Scaffolding protein functional sites
著者Bera, A.K, Watson, J, Baker, D.
登録日2022-07-24
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Scaffolding protein functional sites using deep learning.
Science, 377, 2022
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
著者Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
登録日2020-09-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
著者Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
登録日2020-09-08
公開日2021-10-06
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
8QHP
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BU of 8qhp by Molmil
Cysteine tRNA ligase homodimer
分子名称: Cysteine--tRNA ligase, ZINC ION
著者Pacesa, M, Correia, B.E, Levy, E.D.
登録日2023-09-08
公開日2023-11-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献An atlas of protein homo-oligomerization across domains of life.
Cell, 187, 2024
8OYW
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BU of 8oyw by Molmil
De novo designed rhomboid protease-like fold RPF_9
分子名称: De novo designed soluble Rhomboid protease-like protein, SODIUM ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins.
Biorxiv, 2024
8OYX
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BU of 8oyx by Molmil
De novo designed soluble GPCR-like fold GLF_18
分子名称: De novo designed soluble GPCR-like protein, PHOSPHATE ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins.
Biorxiv, 2024
8OYY
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BU of 8oyy by Molmil
De novo designed soluble GPCR-like fold GLF_32
分子名称: CHLORIDE ION, De novo designed soluble GPCR-like protein, POTASSIUM ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins.
Biorxiv, 2024
8OYV
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BU of 8oyv by Molmil
De novo designed Claudin fold CLF_4
分子名称: De novo designed soluble Claudin
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins.
Biorxiv, 2024
8OYS
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BU of 8oys by Molmil
De novo designed TIM barrel fold TBF_24
分子名称: CHLORIDE ION, De novo designed TIM-barrel
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Computational design of soluble functional analogues of integral membrane proteins.
Biorxiv, 2024
8P49
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BU of 8p49 by Molmil
Uncharacterized Q8U0N8 protein from Pyrococcus furiosus
分子名称: Q8U0N8 protein
著者Pacesa, M, Correia, B.E, Levy, E.D.
登録日2023-05-19
公開日2023-11-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献An atlas of protein homo-oligomerization across domains of life.
Cell, 187, 2024
8Q70
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BU of 8q70 by Molmil
tRNA pseudouridine synthase A homodimer
分子名称: CHLORIDE ION, MAGNESIUM ION, tRNA pseudouridine synthase A
著者Pacesa, M, Correia, B.E, Levy, E.D.
登録日2023-08-15
公開日2023-11-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An atlas of protein homo-oligomerization across domains of life.
Cell, 187, 2024
7K3H
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BU of 7k3h by Molmil
Crystal structure of deep network hallucinated protein 0217
分子名称: Network hallucinated protein 0217
著者Pellock, S.J, Anishchenko, I, Chidyausiku, T.M, Bera, A.K, DiMaio, F, Baker, D.
登録日2020-09-11
公開日2021-12-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
7M0Q
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BU of 7m0q by Molmil
Crystal structure of deep network hallucinated protein 0738_mod
分子名称: Network hallucinated protein 0738_mod
著者Pellock, S.J, Bera, A.K, Anishchenko, I, Baker, D.
登録日2021-03-11
公開日2021-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
7M5T
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BU of 7m5t by Molmil
Solution NMR structure of de novo designed protein 0515
分子名称: De novo designed protein 0515
著者Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T.
登録日2021-03-24
公開日2021-12-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
5V6P
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BU of 5v6p by Molmil
CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1
分子名称: ERAD-associated E3 ubiquitin-protein ligase HRD1
著者Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M.
登録日2017-03-17
公開日2017-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
5V7V
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BU of 5v7v by Molmil
Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M.
登録日2017-03-20
公開日2017-08-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
7DCN
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BU of 7dcn by Molmil
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
分子名称: Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, SULFATE ION, ZINC ION
著者Xu, H, Wang, B, Su, X.D.
登録日2020-10-26
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Co-evolution-based prediction of metal-binding sites in proteomes by machine learning.
Nat.Chem.Biol., 19, 2023
7DCM
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BU of 7dcm by Molmil
Crystal structure of CITX
分子名称: Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, ZINC ION
著者Xu, H, Wang, B, Su, X.D.
登録日2020-10-26
公開日2021-11-03
最終更新日2023-05-17
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Co-evolution-based prediction of metal-binding sites in proteomes by machine learning.
Nat.Chem.Biol., 19, 2023
8UBH
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BU of 8ubh by Molmil
Solution NMR structure of KaiB variant from Thermosynechococcus elongatus vestitus (KaiBTV-4)
分子名称: Circadian oscillation regulator
著者Ojoawo, A, Wayment-Steele, H.K, Kern, D.
登録日2023-09-23
公開日2023-10-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Predicting multiple conformations via sequence clustering and AlphaFold2.
Nature, 625, 2024

 

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