6VJY
Cryo-EM structure of Hrd1/Hrd3 monomer
Summary for 6VJY
Entry DOI | 10.2210/pdb6vjy/pdb |
EMDB information | 21220 |
Descriptor | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 (2 entities in total) |
Functional Keywords | retro-translocon, erad, protein degradation, protein transport |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 138504.98 |
Authors | Wu, X.,Rapoport, T.A. (deposition date: 2020-01-18, release date: 2020-04-29, Last modification date: 2024-03-06) |
Primary citation | Wu, X.,Siggel, M.,Ovchinnikov, S.,Mi, W.,Svetlov, V.,Nudler, E.,Liao, M.,Hummer, G.,Rapoport, T.A. Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368:-, 2020 Cited by PubMed: 32327568DOI: 10.1126/science.aaz2449 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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