8DT0

Scaffolding protein functional sites using deep learning

Summary for 8DT0

• Entry DOI: 10.2210/pdb8dt0/pdb
• Descriptor: Scaffolding protein functional sites (1 entity in total)
• Functional Keywords: de novo design, scaffolding protein functional sites, deep learning, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 30780.29

Authors

Bera, A.K.,Watson, J.,Baker, D. (deposition date: 2022-07-24, release date: 2022-08-10, Last modification date: 2024-04-03)

• Primary citation: Wang, J.,Lisanza, S.,Juergens, D.,Tischer, D.,Watson, J.L.,Castro, K.M.,Ragotte, R.,Saragovi, A.,Milles, L.F.,Baek, M.,Anishchenko, I.,Yang, W.,Hicks, D.R.,Exposit, M.,Schlichthaerle, T.,Chun, J.H.,Dauparas, J.,Bennett, N.,Wicky, B.I.M.,Muenks, A.,DiMaio, F.,Correia, B.,Ovchinnikov, S.,Baker, D.; Scaffolding protein functional sites using deep learning.; Science, 377:387-394, 2022; PubMed: 35862514; DOI: 10.1126/science.abn2100

Experimental method

X-RAY DIFFRACTION (2.46 Å)