7AA4
Structure of ClpC1-NTD bound to a CymA analogue
Summary for 7AA4
Entry DOI | 10.2210/pdb7aa4/pdb |
Descriptor | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue (3 entities in total) |
Functional Keywords | helical receptor domain, cyclomarin a inhibtor, chaperone |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 2 |
Total formula weight | 18323.10 |
Authors | Meinhart, A.,Morreale, F.E.,Kaiser, M.,Clausen, T. (deposition date: 2020-09-03, release date: 2021-08-11, Last modification date: 2024-01-31) |
Primary citation | Morreale, F.E.,Kleine, S.,Leodolter, J.,Junker, S.,Hoi, D.M.,Ovchinnikov, S.,Okun, A.,Kley, J.,Kurzbauer, R.,Junk, L.,Guha, S.,Podlesainski, D.,Kazmaier, U.,Boehmelt, G.,Weinstabl, H.,Rumpel, K.,Schmiedel, V.M.,Hartl, M.,Haselbach, D.,Meinhart, A.,Kaiser, M.,Clausen, T. BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185:2338-, 2022 Cited by PubMed: 35662409DOI: 10.1016/j.cell.2022.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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