7ABR

Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide

Summary for 7ABR

Entry DOI	10.2210/pdb7abr/pdb
EMDB information	11707
Descriptor	Negative regulator of genetic competence ClpC/MecB, substrate polypeptide, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	chaperone, aaa+ protein, protein degradation
Biological source	Bacillus subtilis (strain 168) More
Total number of polymer chains	7
Total formula weight	554730.68
Authors	Morreale, F.E.,Meinhart, A.,Haselbach, D.,Clausen, T. (deposition date: 2020-09-08, release date: 2021-10-06, Last modification date: 2022-07-06)
Primary citation	Morreale, F.E.,Kleine, S.,Leodolter, J.,Junker, S.,Hoi, D.M.,Ovchinnikov, S.,Okun, A.,Kley, J.,Kurzbauer, R.,Junk, L.,Guha, S.,Podlesainski, D.,Kazmaier, U.,Boehmelt, G.,Weinstabl, H.,Rumpel, K.,Schmiedel, V.M.,Hartl, M.,Haselbach, D.,Meinhart, A.,Kaiser, M.,Clausen, T. BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185:2338-, 2022 Cited by PubMed: 35662409 DOI: 10.1016/j.cell.2022.05.009 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation