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8FU6
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BU of 8fu6 by Molmil
GCGR-Gs complex in the presence of RAMP2
分子名称: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K.
登録日2023-01-16
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Negative allosteric modulation of the glucagon receptor by RAMP2.
Cell, 186, 2023
7TQL
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BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
登録日2022-01-26
公開日2022-04-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
2B4C
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BU of 2b4c by Molmil
Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, T-cell surface glycoprotein CD4, ...
著者Huang, C, Tang, M, Zhang, M.Y, Majeed, S, Montabana, E, Stanfield, R.L, Dimitrov, D.S, Korber, B, Sodroski, J, Wilson, I.A, Wyatt, R, Kwong, P.D.
登録日2005-09-23
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
7KJX
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BU of 7kjx by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJV
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BU of 7kjv by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core
分子名称: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJW
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BU of 7kjw by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz
分子名称: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
8T8M
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BU of 8t8m by Molmil
Quis-bound intermediate mGlu5
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nb43
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-22
公開日2023-10-11
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Stepwise activation of a metabotropic glutamate receptor.
Nature, 629, 2024
8T6J
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BU of 8t6j by Molmil
CDPPB-bound inactive mGlu5
分子名称: 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide, Metabotropic glutamate receptor 5
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-16
公開日2023-10-11
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Stepwise activation of a metabotropic glutamate receptor.
Nature, 629, 2024
8T7H
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BU of 8t7h by Molmil
Quis-bound intermediate mGlu5
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nanobody 43
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-20
公開日2023-10-11
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Stepwise activation of a metabotropic glutamate receptor.
Nature, 629, 2024
8TAO
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BU of 8tao by Molmil
Quis and CDPPB bound active mGlu5
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide, Metabotropic glutamate receptor 5, ...
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-27
公開日2023-10-11
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Stepwise activation of a metabotropic glutamate receptor.
Nature, 629, 2024
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-18
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019

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