7KJX
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
Summary for 7KJX
| Entry DOI | 10.2210/pdb7kjx/pdb |
| EMDB information | 22901 |
| Descriptor | Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, HIV-1 viral RNA fragment, ... (6 entities in total) |
| Functional Keywords | reverse transcriptase, rna, protein-rna complex, trna, polymerase, viral protein, viral protein-rna complex, viral protein/rna |
| Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) More |
| Total number of polymer chains | 4 |
| Total formula weight | 132048.61 |
| Authors | Ha, B.,Larsen, K.P.,Zhang, J.,Fu, Z.,Montabana, E.,Jackson, L.N.,Chen, D.H.,Puglisi, E.V. (deposition date: 2020-10-26, release date: 2021-03-17, Last modification date: 2021-05-12) |
| Primary citation | Ha, B.,Larsen, K.P.,Zhang, J.,Fu, Z.,Montabana, E.,Jackson, L.N.,Chen, D.H.,Puglisi, E.V. High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12:2500-2500, 2021 Cited by PubMed: 33947853DOI: 10.1038/s41467-021-22628-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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