8TAO

Quis and CDPPB bound active mGlu5

Summary for 8TAO

Entry DOI	10.2210/pdb8tao/pdb
EMDB information	41139 41789 41793 41796
Descriptor	Metabotropic glutamate receptor 5, Nb43, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ... (4 entities in total)
Functional Keywords	gpcr, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	225188.59
Authors	Krishna Kumar, K.,Wang, H.,Kobilka, B.K. (deposition date: 2023-06-27, release date: 2023-10-11, Last modification date: 2024-06-05)
Primary citation	Krishna Kumar, K.,Wang, H.,Habrian, C.,Latorraca, N.R.,Xu, J.,O'Brien, E.S.,Zhang, C.,Montabana, E.,Koehl, A.,Marqusee, S.,Isacoff, E.Y.,Kobilka, B.K. Stepwise activation of a metabotropic glutamate receptor. Nature, 629:951-956, 2024 Cited by PubMed: 38632403 DOI: 10.1038/s41586-024-07327-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation