7TQL
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
Summary for 7TQL
Entry DOI | 10.2210/pdb7tql/pdb |
EMDB information | 26067 |
Descriptor | Eukaryotic translation initiation factor 5B, 40S ribosomal protein S7, 40S ribosomal protein S8, ... (40 entities in total) |
Functional Keywords | eif5b, translation, initiation, eif1a, ribosome |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 38 |
Total formula weight | 1234819.23 |
Authors | Lapointe, C.P.,Grosely, R.,Sokabe, M.,Alvarado, C.,Wang, J.,Montabana, E.,Villa, N.,Shin, B.,Dever, T.,Fraser, C.,Fernandez, I.S.,Puglisi, J.D. (deposition date: 2022-01-26, release date: 2022-04-27, Last modification date: 2024-06-12) |
Primary citation | Lapointe, C.P.,Grosely, R.,Sokabe, M.,Alvarado, C.,Wang, J.,Montabana, E.,Villa, N.,Shin, B.S.,Dever, T.E.,Fraser, C.S.,Fernandez, I.S.,Puglisi, J.D. eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607:185-190, 2022 Cited by PubMed: 35732735DOI: 10.1038/s41586-022-04858-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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