Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1KD8
DownloadVisualize
BU of 1kd8 by Molmil
X-RAY STRUCTURE OF THE COILED COIL GCN4 ACID BASE HETERODIMER ACID-d12Ia16V BASE-d12La16L
分子名称: GCN4 ACID BASE HETERODIMER ACID-d12Ia16V, GCN4 ACID BASE HETERODIMER BASE-d12La16L
著者Keating, A.E, Malashkevich, V.N, Tidor, B, Kim, P.S.
登録日2001-11-12
公開日2001-11-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils.
Proc.Natl.Acad.Sci.USA, 98, 2001
1KD9
DownloadVisualize
BU of 1kd9 by Molmil
X-RAY STRUCTURE OF THE COILED COIL GCN4 ACID BASE HETERODIMER ACID-d12La16L BASE-d12La16L
分子名称: GCN4 ACID BASE HETERODIMER ACID-d12La16L, GCN4 ACID BASE HETERODIMER BASE-d12La16L
著者Keating, A.E, Malashkevich, V.N, Tidor, B, Kim, P.S.
登録日2001-11-12
公開日2001-11-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils.
Proc.Natl.Acad.Sci.USA, 98, 2001
1KDD
DownloadVisualize
BU of 1kdd by Molmil
X-ray structure of the coiled coil GCN4 ACID BASE HETERODIMER ACID-d12La16I BASE-d12La16L
分子名称: GCN4 ACID BASE HETERODIMER ACID-d12La16I, GCN4 ACID BASE HETERODIMER BASE-d12La16L
著者Keating, A.E, Malashkevich, V.N, Tidor, B, Kim, P.S.
登録日2001-11-12
公開日2001-11-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils.
Proc.Natl.Acad.Sci.USA, 98, 2001
7LXE
DownloadVisualize
BU of 7lxe by Molmil
ENAH EVH1 domain bound to peptide from ABI1
分子名称: Protein enabled homolog,Abl interactor 1
著者Keating, A.E, Grant, R.A, Hwang, T.H.
登録日2021-03-03
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH.
Elife, 11, 2022
6MBB
DownloadVisualize
BU of 6mbb by Molmil
Human Bfl-1 in complex with the designed peptide dF1
分子名称: Bcl-2-related protein A1, dF1
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6E3J
DownloadVisualize
BU of 6e3j by Molmil
Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F10
分子名称: Bcl-2-related protein A1, SULFATE ION, peptide srt.F10
著者Jenson, J.M, Keating, A.E.
登録日2018-07-14
公開日2018-10-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.482 Å)
主引用文献Peptide design by optimization on a data-parameterized protein interaction landscape.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E3I
DownloadVisualize
BU of 6e3i by Molmil
Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F4
分子名称: Bcl-2-related protein A1, SULFATE ION, peptide srt.F4
著者Jenson, J.M, Keating, A.E.
登録日2018-07-14
公開日2018-10-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.481 Å)
主引用文献Peptide design by optimization on a data-parameterized protein interaction landscape.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3MK8
DownloadVisualize
BU of 3mk8 by Molmil
The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1
著者Stewart, M, Fire, E, Keating, A.E, Walensky, L.D.
登録日2010-04-14
公開日2010-06-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.321 Å)
主引用文献The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
Nat.Chem.Biol., 6, 2010
1XOF
DownloadVisualize
BU of 1xof by Molmil
Heterooligomeric Beta Beta Alpha Miniprotein
分子名称: BBAhetT1
著者Ali, M.H, Taylor, C.M, Grigoryan, G, Allen, K.N, Imperiali, B, Keating, A.E.
登録日2004-10-06
公開日2005-02-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Design of a Heterospecific, Tetrameric, 21-Residue Miniprotein with Mixed alpha/beta Structure.
Structure, 13, 2005
6UA3
DownloadVisualize
BU of 6ua3 by Molmil
Human Mcl-1 in complex with a modified Bim BH3 peptide
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, modified Bim BH3 peptide
著者Mandal, T, Grant, R.A, Keating, A.E.
登録日2019-09-10
公開日2020-09-16
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Inhibitor peptides against Mcl-1 containing non-natural amino acids show potent apoptotic response.
To Be Published
6UAB
DownloadVisualize
BU of 6uab by Molmil
Human Mcl-1 in complex with a modified unnatural Bim BH3 peptide
分子名称: ADAMANTANE, Induced myeloid leukemia cell differentiation protein Mcl-1, modified unnatural Bim BH3 peptide
著者Mandal, T, Grant, R.A, Keating, A.E.
登録日2019-09-10
公開日2020-09-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inhibitor peptides against Mcl-1 containing non-natural amino acids show potent apoptotic response.
To Be Published
6MBE
DownloadVisualize
BU of 6mbe by Molmil
Human Mcl-1 in complex with the designed peptide dM7
分子名称: CHLORIDE ION, Induced myeloid leukemia cell differentiation protein Mcl-1, dM7
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6MBD
DownloadVisualize
BU of 6mbd by Molmil
Human Mcl-1 in complex with the designed peptide dM1
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, dM1
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6MBC
DownloadVisualize
BU of 6mbc by Molmil
Human Bfl-1 in complex with the designed peptide dF4
分子名称: Bcl-2-related protein A1, dF4
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
5W89
DownloadVisualize
BU of 5w89 by Molmil
Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-18
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-18
著者Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-06-21
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W8F
DownloadVisualize
BU of 5w8f by Molmil
Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-14
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-14
著者Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-06-21
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7LXF
DownloadVisualize
BU of 7lxf by Molmil
ENAH EVH1 domain bound to peptide from protein PCARE
分子名称: Protein enabled homolog,Photoreceptor cilium actin regulator
著者Hwang, T, Grant, R.A, Keating, A.E.
登録日2021-03-03
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
Elife, 10, 2021
2PQK
DownloadVisualize
BU of 2pqk by Molmil
X-ray crystal structure of human Mcl-1 in complex with Bim BH3
分子名称: Bim BH3 peptide, Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ...
著者Bare, E, Grant, R.A, Keating, A.E.
登録日2007-05-02
公開日2007-06-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3KJ0
DownloadVisualize
BU of 3kj0 by Molmil
Mcl-1 in complex with Bim BH3 mutant I2dY
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Fire, E, Grant, R.A, Keating, A.E.
登録日2009-11-02
公開日2010-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3KJ1
DownloadVisualize
BU of 3kj1 by Molmil
Mcl-1 in complex with Bim BH3 mutant I2dA
分子名称: ACETATE ION, Bcl-2-like protein 11, CHLORIDE ION, ...
著者Fire, E, Grant, R.A, Keating, A.E.
登録日2009-11-02
公開日2010-02-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3KZ0
DownloadVisualize
BU of 3kz0 by Molmil
MCL-1 complex with MCL-1-specific selected peptide
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 specific peptide MB7, SULFATE ION, ...
著者Dutta, S, Fire, E, Grant, R.A, Sauer, R.T, Keating, A.E.
登録日2009-12-07
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL.
J.Mol.Biol., 398, 2010
3KJ2
DownloadVisualize
BU of 3kj2 by Molmil
Mcl-1 in complex with Bim BH3 mutant F4aE
分子名称: ACETATE ION, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ...
著者Fire, E, Grant, R.A, Keating, A.E.
登録日2009-11-02
公開日2010-02-16
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
8CZH
DownloadVisualize
BU of 8czh by Molmil
Human BAK in complex with the dM2 peptide
分子名称: Bcl-2 homologous antagonist/killer, DM2 peptide
著者Aguilar, F, Keating, A.E.
登録日2022-05-24
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.
Structure, 31, 2023
8CZF
DownloadVisualize
BU of 8czf by Molmil
Human BAK in complex with the dF2 peptide
分子名称: Bcl-2 homologous antagonist/killer, DF2 peptide
著者Aguilar, F, Keating, A.E.
登録日2022-05-24
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.
Structure, 31, 2023
8CZG
DownloadVisualize
BU of 8czg by Molmil
Human BAK in complex with the dF3 peptide
分子名称: Bcl-2 homologous antagonist/killer, dF3 peptide
著者Aguilar, F, Keating, A.E.
登録日2022-05-24
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.
Structure, 31, 2023

 

12>

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon