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PDB: 5 results

3KJ0
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BU of 3kj0 by Molmil
Mcl-1 in complex with Bim BH3 mutant I2dY
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Fire, E, Grant, R.A, Keating, A.E.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3KJ1
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BU of 3kj1 by Molmil
Mcl-1 in complex with Bim BH3 mutant I2dA
Descriptor: ACETATE ION, Bcl-2-like protein 11, CHLORIDE ION, ...
Authors:Fire, E, Grant, R.A, Keating, A.E.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.945 Å)
Cite:Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3KJ2
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BU of 3kj2 by Molmil
Mcl-1 in complex with Bim BH3 mutant F4aE
Descriptor: ACETATE ION, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ...
Authors:Fire, E, Grant, R.A, Keating, A.E.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
3MK8
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BU of 3mk8 by Molmil
The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Stewart, M, Fire, E, Keating, A.E, Walensky, L.D.
Deposit date:2010-04-14
Release date:2010-06-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.321 Å)
Cite:The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
Nat.Chem.Biol., 6, 2010
3KZ0
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BU of 3kz0 by Molmil
MCL-1 complex with MCL-1-specific selected peptide
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 specific peptide MB7, SULFATE ION, ...
Authors:Dutta, S, Fire, E, Grant, R.A, Sauer, R.T, Keating, A.E.
Deposit date:2009-12-07
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL.
J.Mol.Biol., 398, 2010

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