8CZG

Human BAK in complex with the dF3 peptide

Summary for 8CZG

• Entry DOI: 10.2210/pdb8czg/pdb
• Descriptor: Bcl-2 homologous antagonist/killer, dF3 peptide (3 entities in total)
• Functional Keywords: bak, inhibitor, bcl-2 family, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 87246.14

Authors

Aguilar, F.,Keating, A.E. (deposition date: 2022-05-24, release date: 2023-01-11, Last modification date: 2023-10-25)

• Primary citation: Aguilar, F.,Yu, S.,Grant, R.A.,Swanson, S.,Ghose, D.,Su, B.G.,Sarosiek, K.A.,Keating, A.E.; Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.; Structure, 31:265-281.e7, 2023; PubMed: 36706751; DOI: 10.1016/j.str.2023.01.001

Experimental method

X-RAY DIFFRACTION (1.99 Å)