6MBC

Human Bfl-1 in complex with the designed peptide dF4

Summary for 6MBC

• Entry DOI: 10.2210/pdb6mbc/pdb
• Descriptor: Bcl-2-related protein A1, dF4 (3 entities in total)
• Functional Keywords: anti-apoptotic bcl-2, inhibitor, design, apoptosis
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 20255.22

Authors

Jenson, J.M.,Keating, A.E. (deposition date: 2018-08-29, release date: 2019-03-06, Last modification date: 2020-01-01)

• Primary citation: Frappier, V.,Jenson, J.M.,Zhou, J.,Grigoryan, G.,Keating, A.E.; Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.; Structure, 27:606-617.e5, 2019; PubMed: 30773399; DOI: 10.1016/j.str.2019.01.008

Experimental method

X-RAY DIFFRACTION (1.752 Å)