6UAB

Human Mcl-1 in complex with a modified unnatural Bim BH3 peptide

Summary for 6UAB

• Entry DOI: 10.2210/pdb6uab/pdb
• Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, modified unnatural Bim BH3 peptide, ADAMANTANE, ... (4 entities in total)
• Functional Keywords: inhibitor, peptide binding protein, peptide binding protein-inhibitor complex, peptide binding protein/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 20480.37

Authors

Mandal, T.,Grant, R.A.,Keating, A.E. (deposition date: 2019-09-10, release date: 2020-09-16)

• Primary citation: Mandal, T.,Grant, R.A.,Keating, A.E.; Inhibitor peptides against Mcl-1 containing non-natural amino acids show potent apoptotic response.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)