6UAB
Human Mcl-1 in complex with a modified unnatural Bim BH3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17823.3 | 1 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (B) | modified unnatural Bim BH3 peptide | polymer | 23 | 2520.9 | 1 | Pfam (PF08945) UniProt (by SIFTS) (O43521) | Homo sapiens | |
| 3 | C (B) | ADAMANTANE | non-polymer | 136.2 | 1 | Chemie (ADM) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A: 172 - 325 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | - | expression tag |
| Ser 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20344.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 136.2 | |
| All* | Total formula weight | 20480.4 |
