6E3I
Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F4
Summary for 6E3I
| Entry DOI | 10.2210/pdb6e3i/pdb |
| Descriptor | Bcl-2-related protein A1, peptide srt.F4, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | anti-apoptotic bcl-2, inhibitor, design, apoptosis |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 19877.60 |
| Authors | Jenson, J.M.,Keating, A.E. (deposition date: 2018-07-14, release date: 2018-10-17, Last modification date: 2020-01-01) |
| Primary citation | Jenson, J.M.,Xue, V.,Stretz, L.,Mandal, T.,Reich, L.L.,Keating, A.E. Peptide design by optimization on a data-parameterized protein interaction landscape. Proc. Natl. Acad. Sci. U.S.A., 115:E10342-E10351, 2018 Cited by PubMed: 30322927DOI: 10.1073/pnas.1812939115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.481 Å) |
Structure validation
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