5T3Z
 
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4PWX
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5BW8
 | | 2.8 A crystal structure of a Get3-Get4-Get5 intermediate complex from S.cerevisiae | | 分子名称: | ATPase GET3, Golgi to ER traffic protein 4, Ubiquitin-like protein MDY2, ... | | 著者 | Gristick, H.B, Chartron, J.W, Clemons, W.M. | | 登録日 | 2015-06-06 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting.
J.Biol.Chem., 290, 2015
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5BWK
 | | 6.0 A Crystal structure of a Get3-Get4-Get5 intermediate complex from S.cerevisiae | | 分子名称: | ATPase GET3, Golgi to ER traffic protein 4, Ubiquitin-like protein MDY2, ... | | 著者 | Gristick, H.B, Chartron, J.W, Clemons, W.M. | | 登録日 | 2015-06-08 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting.
J.Biol.Chem., 290, 2015
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5T3X
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7TQG
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6ORQ
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... | | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6ORP
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... | | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6ORO
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... | | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6ORN
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 | | 分子名称: | 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6UDK
 | | HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | | 分子名称: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-09-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
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6UDJ
 | | HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | | 分子名称: | 1-18 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-09-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
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6UTA
 | | Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII | | 分子名称: | Env, Z004 iGL Fab heavy chain, Z004 iGL Fab light chain | | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6UTE
 | | Crystal structure of Z032 Fab in complex with WNV EDIII | | 分子名称: | Envelope domain III, GLYCEROL, Z032 Fab heavy chain, ... | | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5UEL
 | | Crystal structure of 354NC102 Fab | | 分子名称: | 354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION | | 著者 | Sievers, S.A, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-01-02 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
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5VIC
 | | Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII | | 分子名称: | Dengue 1 Envelope DIII domain, Fab heavy chain, Fab light chain | | 著者 | Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-04-14 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
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5VVF
 | | Crystal Structure of 354BG1 Fab | | 分子名称: | 1,2-ETHANEDIOL, 354BG1 Heavy Chain, 354BG1 Light Chain | | 著者 | Scharf, L, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-05-19 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
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5UEM
 | | Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 354NC37 Fab Heavy Chain, ... | | 著者 | Sievers, S.A, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-01-02 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
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5VIG
 | | Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII | | 分子名称: | CITRATE ANION, Fab heavy chain, Fab light chain, ... | | 著者 | Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-04-16 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
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7MXE
 | | Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... | | 著者 | Abernathy, M.E, Bjorkman, P.J. | | 登録日 | 2021-05-19 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.
Npj Vaccines, 6, 2021
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9BGE
 | | Cryo-EM structure of mAb8-24 bound to 426c.WITO.TM.SOSIP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.WITO.TM.SOSIP, ... | | 著者 | Hurlburt, N.K, Pancera, M. | | 登録日 | 2024-04-18 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env.
J.Virol., 98, 2024
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6XCM
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6XCA
 | | Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105 | | 分子名称: | C105 Heavy Chain, C105 Light Chain, SULFATE ION | | 著者 | Sharaf, N.G, Barnes, C.O, Bjorkman, P.J. | | 登録日 | 2020-06-08 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
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6XCN
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5THR
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