5UEM

Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120

Summary for 5UEM

• Entry DOI: 10.2210/pdb5uem/pdb
• Related: 5UEL
• Descriptor: clade A/E 93TH057 HIV-1 gp120 core, 354NC37 Fab Heavy Chain, 354NC37 Fab Light Chain, ... (9 entities in total)
• Functional Keywords: hiv, envelope protein, antibody, immunity, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 3
• Total formula weight: 92209.13

Authors

Sievers, S.A.,Gristick, H.B.,Bjorkman, P.J. (deposition date: 2017-01-02, release date: 2018-01-10, Last modification date: 2023-10-04)

• Primary citation: Freund, N.T.,Wang, H.,Scharf, L.,Nogueira, L.,Horwitz, J.A.,Bar-On, Y.,Golijanin, J.,Sievers, S.A.,Sok, D.,Cai, H.,Cesar Lorenzi, J.C.,Halper-Stromberg, A.,Toth, I.,Piechocka-Trocha, A.,Gristick, H.B.,van Gils, M.J.,Sanders, R.W.,Wang, L.X.,Seaman, M.S.,Burton, D.R.,Gazumyan, A.,Walker, B.D.,West, A.P.,Bjorkman, P.J.,Nussenzweig, M.C.; Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.; Sci Transl Med, 9:-, 2017; PubMed: 28100831; DOI: 10.1126/scitranslmed.aal2144

Experimental method

X-RAY DIFFRACTION (2.7 Å)