6XCA

Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105

Summary for 6XCA

• Entry DOI: 10.2210/pdb6xca/pdb
• Descriptor: C105 Heavy Chain, C105 Light Chain, SULFATE ION, ... (4 entities in total)
• Functional Keywords: antibody, sars-cov-2, sars2, coronavirus, neutralizing, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47705.78

Authors

Sharaf, N.G.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-06-08, release date: 2020-07-01, Last modification date: 2023-10-18)

• Primary citation: Barnes, C.O.,West Jr., A.P.,Huey-Tubman, K.E.,Hoffmann, M.A.G.,Sharaf, N.G.,Hoffman, P.R.,Koranda, N.,Gristick, H.B.,Gaebler, C.,Muecksch, F.,Lorenzi, J.C.C.,Finkin, S.,Hagglof, T.,Hurley, A.,Millard, K.G.,Weisblum, Y.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Caskey, M.,Robbiani, D.F.,Nussenzweig, M.C.,Bjorkman, P.J.; Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.; Cell, 182:828-, 2020; PubMed: 32645326; DOI: 10.1016/j.cell.2020.06.025

Experimental method

X-RAY DIFFRACTION (1.8 Å)