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7NXX
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BU of 7nxx by Molmil
Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2).
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C.
登録日2021-03-19
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1
To Be Published
6SL6
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BU of 6sl6 by Molmil
p53 charged core
分子名称: Cellular tumor antigen p53, GLYCEROL, ZINC ION
著者Gallardo, R, Langenberg, T, Schymkowitz, J, Rousseau, F, Ulens, C.
登録日2019-08-18
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins.
Cell Rep, 31, 2020
5FR3
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BU of 5fr3 by Molmil
X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)
分子名称: CALCIUM ION, GLYCEROL, PROTECTIVE ANTIGEN
著者Ganesan, A, Siekierska, A, Beerten, J, Brams, M, van Durme, J, De Baets, G, van der Kant, R, Gallardo, R, Ramakers, M, Langenberg, T, Wilkinson, H, De Smet, F, Ulens, C, Rousseau, F, Schymkowitz, J.
登録日2015-12-15
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.935 Å)
主引用文献Structural Hot Spots for the Solubility of Globular Proteins
Nat.Commun., 7, 2016
4Z33
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BU of 4z33 by Molmil
Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
分子名称: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
著者Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P.
登録日2015-03-30
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
6ZRF
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BU of 6zrf by Molmil
amyloid structure of amylin (IAPP - islet amyloid polypeptide)
分子名称: Islet amyloid polypeptide
著者Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
登録日2020-07-13
公開日2020-09-30
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
6ZRQ
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BU of 6zrq by Molmil
two-protofilament amyloid structure of S20G variant of human amylin (IAPP - islet amyloid polypeptide)
分子名称: Islet amyloid polypeptide
著者Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
登録日2020-07-14
公開日2020-09-30
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
6ZRR
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BU of 6zrr by Molmil
three-protofilament amyloid structure of S20G variant of human amylin (IAPP - Islet Amyloid Polypeptide)
分子名称: Islet amyloid polypeptide
著者Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
登録日2020-07-14
公開日2020-09-30
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
8OHI
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BU of 8ohi by Molmil
Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril
分子名称: Microtubule-associated protein tau
著者Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
登録日2023-03-21
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OH2
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BU of 8oh2 by Molmil
Structure of the Tau-PAM4 Type 1 amyloid fibril
分子名称: Microtubule-associated protein tau
著者Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
登録日2023-03-20
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OHP
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BU of 8ohp by Molmil
Structure of the Fmoc-Tau-PAM4 Type 3 amyloid fibril
分子名称: Microtubule-associated protein tau
著者Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
登録日2023-03-21
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OI0
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BU of 8oi0 by Molmil
Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril
分子名称: Microtubule-associated protein tau
著者Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
登録日2023-03-21
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8A7O
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BU of 8a7o by Molmil
beta-2-microglobulin DeltaN6 amyloid fibril form 2PFa
分子名称: Beta-2-microglobulin form pI 5.3
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8A7T
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BU of 8a7t by Molmil
beta-2-microglobulin D76N amyloid fibril form 2PFa
分子名称: Beta-2-microglobulin
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8A7P
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BU of 8a7p by Molmil
beta-2-microglobulin DeltaN6 amyloid fibril form 2PFb
分子名称: Beta-2-microglobulin form pI 5.3
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8A7Q
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BU of 8a7q by Molmil
beta-2-microglobulin V27M amyloid fibril form 4PF
分子名称: Beta-2-microglobulin
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
6HLU
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BU of 6hlu by Molmil
Crystal structure of the LRR-Roc-COR domain of the Chlorobium tepidum Roco protein
分子名称: Rab family protein
著者Deyaert, E, Versees, W, Singh, R.
登録日2018-09-11
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structure and nucleotide-induced conformational dynamics of theChlorobium tepidumRoco protein.
Biochem. J., 476, 2019
6RMV
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BU of 6rmv by Molmil
The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer
分子名称: GLYCEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Gruss, F, Oberwinkler, J, Ulens, C.
登録日2019-05-07
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels.
Proc.Natl.Acad.Sci.USA, 117, 2020
4N8C
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BU of 4n8c by Molmil
Three-dimensional structure of the extracellular domain of Matrix protein 2 of influenza A virus
分子名称: Extracellular domain of influenza Matrix protein 2, Heavy chain of monoclonal antibody, Light chain of monoclonal antibody
著者Cho, K.J, Seok, J.H, Kim, S, Roose, K, Schepens, B, Fiers, W, Saelens, X, Kim, K.H.
登録日2013-10-17
公開日2014-10-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody
J.Virol., 89, 2015
8AWT
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BU of 8awt by Molmil
IAPP S20G lag-phase fibril polymorph 2PF-P
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-08-30
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ3
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BU of 8az3 by Molmil
IAPP S20G growth-phase fibril polymorph 4PF-CU
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ5
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BU of 8az5 by Molmil
IAPP S20G plateau-phase fibril polymorph 4PF-CU
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ4
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BU of 8az4 by Molmil
IAPP S20G plateau-phase fibril polymorph 2PF-L
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ7
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BU of 8az7 by Molmil
IAPP S20G plateau-phase fibril polymorph 4PF-LJ
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ6
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BU of 8az6 by Molmil
IAPP S20G plateau-phase fibril polymorph 4PF-LU
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
8AZ0
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BU of 8az0 by Molmil
IAPP S20G growth-phase fibril polymorph 2PF-L
分子名称: Islet amyloid polypeptide
著者Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-09-05
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023

 

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