6ZRR
three-protofilament amyloid structure of S20G variant of human amylin (IAPP - Islet Amyloid Polypeptide)
Summary for 6ZRR
| Entry DOI | 10.2210/pdb6zrr/pdb |
| Related | 6ZRF 6ZRQ |
| EMDB information | 11380 11382 11383 |
| Descriptor | Islet amyloid polypeptide (1 entity in total) |
| Functional Keywords | amyloid fibril type-2-diabetes early-onset, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 18 |
| Total formula weight | 69809.27 |
| Authors | Gallardo, R.U.,Iadanza, M.G.,Ranson, N.A.,Radford, S.E. (deposition date: 2020-07-14, release date: 2020-09-30, Last modification date: 2020-11-18) |
| Primary citation | Gallardo, R.,Iadanza, M.G.,Xu, Y.,Heath, G.R.,Foster, R.,Radford, S.E.,Ranson, N.A. Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nat.Struct.Mol.Biol., 27:1048-1056, 2020 Cited by PubMed: 32929282DOI: 10.1038/s41594-020-0496-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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