6RMV
The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer
Summary for 6RMV
Entry DOI | 10.2210/pdb6rmv/pdb |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Transient receptor potential cation channel, subfamily M, member 3, ... (5 entities in total) |
Functional Keywords | g protein, trp channel, inhibitor, protein binding |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 47286.39 |
Authors | Gruss, F.,Oberwinkler, J.,Ulens, C. (deposition date: 2019-05-07, release date: 2020-10-14, Last modification date: 2024-01-24) |
Primary citation | Behrendt, M.,Gruss, F.,Enzeroth, R.,Dembla, S.,Zhao, S.,Crassous, P.A.,Mohr, F.,Nys, M.,Louros, N.,Gallardo, R.,Zorzini, V.,Wagner, D.,Economou, A.,Rousseau, F.,Schymkowitz, J.,Philipp, S.E.,Rohacs, T.,Ulens, C.,Oberwinkler, J. The structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels. Proc.Natl.Acad.Sci.USA, 117:29090-29100, 2020 Cited by PubMed: 33122432DOI: 10.1073/pnas.2001177117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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