7NXX

Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2).

Summary for 7NXX

• Entry DOI: 10.2210/pdb7nxx/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], nanobody 2, COPPER (II) ION, ... (4 entities in total)
• Functional Keywords: cu/zn superoxide dismutase metalloenzyme binding catalysing the dismutation of superoxides into hydrogen peroxide, metal binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30708.80

Authors

Gallardo, R.,Rousseau, F.,Schymkowitz, J.,Ulens, C. (deposition date: 2021-03-19, release date: 2022-09-28, Last modification date: 2024-01-31)

• Primary citation: van der Kant, R.,Gallardo, R.,Michiels, E.,Wilkinson, H.,Claes, F.,Laird, A.,Van Den Bosch, L.,Robberecht, W.,Ghassabeh, G.H.,Oliveberg, M.,Ulens, C.,Schymkowitz, J.,Rousseau, F.; Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.189 Å)