8A7Q

beta-2-microglobulin V27M amyloid fibril form 4PF

Summary for 8A7Q

• Entry DOI: 10.2210/pdb8a7q/pdb
• Related: 8A7O 8A7P 8A7T
• EMDB information: 15222 15223 15224 15225 15226 15227
• Descriptor: Beta-2-microglobulin (1 entity in total)
• Functional Keywords: amyloid, fibril, helical, cross-beta, dialysis-related amyloidosis, polymorph, b2m, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 141362.71

Authors

Wilkinson, M.,Gallardo, R.,Radford, S.E.,Ranson, N.A. (deposition date: 2022-06-21, release date: 2023-03-22)

• Primary citation: Wilkinson, M.,Gallardo, R.U.,Martinez, R.M.,Guthertz, N.,So, M.,Aubrey, L.D.,Radford, S.E.,Ranson, N.A.; Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.; Nat Commun, 14:1190-1190, 2023; PubMed: 36864041; DOI: 10.1038/s41467-023-36791-8

Experimental method

ELECTRON MICROSCOPY (2.8 Å)