6ZRF
amyloid structure of amylin (IAPP - islet amyloid polypeptide)
Summary for 6ZRF
| Entry DOI | 10.2210/pdb6zrf/pdb |
| EMDB information | 11380 |
| Descriptor | Islet amyloid polypeptide (1 entity in total) |
| Functional Keywords | amyloid fibril type-2-diabetes hormone, protein fibril |
| Biological source | synthetic construct |
| Total number of polymer chains | 12 |
| Total formula weight | 46899.83 |
| Authors | Gallardo, R.U.,Iadanza, M.G.,Ranson, N.A.,Radford, S.E. (deposition date: 2020-07-13, release date: 2020-09-30, Last modification date: 2020-11-18) |
| Primary citation | Gallardo, R.,Iadanza, M.G.,Xu, Y.,Heath, G.R.,Foster, R.,Radford, S.E.,Ranson, N.A. Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nat.Struct.Mol.Biol., 27:1048-1056, 2020 Cited by PubMed: 32929282DOI: 10.1038/s41594-020-0496-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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