8AZ4
IAPP S20G plateau-phase fibril polymorph 2PF-L
Summary for 8AZ4
Entry DOI | 10.2210/pdb8az4/pdb |
Related | 8AZ0 |
EMDB information | 15728 15753 15754 15755 15756 |
Descriptor | Islet amyloid polypeptide (2 entities in total) |
Functional Keywords | amyloid, fibril, helical, cross-beta, amylin, polymorph, islet, protein fibril, diabetes |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 10 |
Total formula weight | 38772.86 |
Authors | Wilkinson, M.,Xu, Y.,Gallardo, R.,Radford, S.E.,Ranson, N.A. (deposition date: 2022-09-05, release date: 2024-01-10) |
Primary citation | Wilkinson, M.,Xu, Y.,Thacker, D.,Taylor, A.I.P.,Fisher, D.G.,Gallardo, R.U.,Radford, S.E.,Ranson, N.A. Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186:5798-5811.e26, 2023 Cited by PubMed: 38134875DOI: 10.1016/j.cell.2023.11.025 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.2 Å) |
Structure validation
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