8AZ3

IAPP S20G growth-phase fibril polymorph 4PF-CU

Summary for 8AZ3

Entry DOI	10.2210/pdb8az3/pdb
Related	8AZ0 8AZ1 8AZ2
EMDB information	15728 15729 15730 15731 15754
Descriptor	Islet amyloid polypeptide (1 entity in total)
Functional Keywords	amyloid, fibril, helical, cross-beta, amylin, polymorph, islet, protein fibril, diabetes
Biological source	Homo sapiens (human)
Total number of polymer chains	20
Total formula weight	77545.72
Authors	Wilkinson, M.,Xu, Y.,Gallardo, R.,Radford, S.E.,Ranson, N.A. (deposition date: 2022-09-05, release date: 2024-01-10)
Primary citation	Wilkinson, M.,Xu, Y.,Thacker, D.,Taylor, A.I.P.,Fisher, D.G.,Gallardo, R.U.,Radford, S.E.,Ranson, N.A. Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186:5798-5811.e26, 2023 Cited by PubMed: 38134875 DOI: 10.1016/j.cell.2023.11.025 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation