2IF7
 
 | | Crystal Structure of NTB-A | | 分子名称: | CALCIUM ION, CHLORIDE ION, SLAM family member 6 | | 著者 | Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C. | | 登録日 | 2006-09-20 | | 公開日 | 2006-10-17 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
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2OYP
 | | T Cell Immunoglobulin Mucin-3 Crystal Structure Revealed a Galectin-9-independent Binding Surface | | 分子名称: | Hepatitis A virus cellular receptor 2, SULFATE ION | | 著者 | Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-02-22 | | 公開日 | 2007-04-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
Immunity, 26, 2007
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6PZT
 | | cryo-EM structure of human NKCC1 | | 分子名称: | Solute carrier family 12 member 2 | | 著者 | Cao, E, Wang, Q, Yang, X. | | 登録日 | 2019-08-01 | | 公開日 | 2020-03-25 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy.
Nat Commun, 11, 2020
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3J5Q
 | | Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy | | 分子名称: | Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1 | | 著者 | Liao, M, Cao, E, Julius, D, Cheng, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
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3J5R
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6WB8
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1NPU
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1 | | 分子名称: | Programmed cell death protein 1 | | 著者 | Zhang, X, Schwartz, J.-C.D, Guo, X, Cao, E, Chen, L, Zhang, Z.-Y, Nathenson, S.G, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2003-01-20 | | 公開日 | 2004-03-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
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3J5P
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3BP5
 | | Crystal structure of the mouse PD-1 and PD-L2 complex | | 分子名称: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-18 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BP6
 | | Crystal structure of the mouse PD-1 Mutant and PD-L2 complex | | 分子名称: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-18 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
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3BOV
 | | Crystal structure of the receptor binding domain of mouse PD-L2 | | 分子名称: | FORMIC ACID, Programmed cell death 1 ligand 2, SODIUM ION | | 著者 | Lazar-Molnar, E, Ramagopal, U, Cao, E, Toro, R, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-12-17 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.USA, 105, 2008
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5T4D
 | | Cryo-EM structure of Polycystic Kidney Disease protein 2 (PKD2), residues 198-703 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hPKD:198-703, Polycystin-2 | | 著者 | Shen, P.S, Yang, X, DeCaen, P.G, Liu, X, Bulkley, D, Clapham, D.E, Cao, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-11-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.
Cell, 167, 2016
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6D1W
 | | human PKD2 F604P mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | | 著者 | Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E. | | 登録日 | 2018-04-12 | | 公開日 | 2018-06-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
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5IS0
 | | Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc | | 分子名称: | Transient receptor potential cation channel subfamily V member 1, capsazepine | | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | | 登録日 | 2016-03-15 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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5IRX
 | | Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc | | 分子名称: | (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | | 登録日 | 2016-03-14 | | 公開日 | 2016-05-25 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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5IRZ
 | | Structure of TRPV1 determined in lipid nanodisc | | 分子名称: | (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | | 登録日 | 2016-03-15 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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3SBW
 | | Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1 | | 分子名称: | Programmed cell death 1 ligand 1, Programmed cell death protein 1 | | 著者 | Lazar-Molnar, E, Ramagopal, U.A, Cao, E, Nathenson, S.G, Almo, S.C. | | 登録日 | 2011-06-06 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
To be published
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2PKD
 | | Crystal structure of CD84: Insite into SLAM family function | | 分子名称: | CHLORIDE ION, SLAM family member 5 | | 著者 | Yan, Q, Malashkevich, V.N, Fedorov, A, Cao, E, Lary, J.W, Cole, J.L, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-04-17 | | 公開日 | 2007-06-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | | 主引用文献 | Structure of CD84 provides insight into SLAM family function.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3RNK
 | | Crystal structure of the complex between mouse PD-1 mutant and PD-L2 IgV domain | | 分子名称: | Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Lazar-Molnar, E, Ramagopal, U.A, Cao, E, Nathenson, S.G, Almo, S.C. | | 登録日 | 2011-04-22 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of the complex between mouse PD-1 mutant and PD-L2 IgV domain
To be Published
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7TTI
 | | Human KCC1 bound with VU0463271 In an outward-open state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-cyclopropyl-N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide, Solute carrier family 12 member 4 | | 著者 | Zhao, Y.X, Cao, E.H. | | 登録日 | 2022-02-01 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TTH
 | | Human potassium-chloride cotransporter 1 in inward-open state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, Solute carrier family 12 member 4 | | 著者 | Zhao, Y.X, Cao, E.H. | | 登録日 | 2022-02-01 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structure of the human cation-chloride cotransport KCC1 in an outward-open state.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7S1X
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7S1Z
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7S1Y
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3J9J
 | | Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy | | 分子名称: | Transient receptor potential cation channel subfamily V member 1 | | 著者 | Wang, R.Y.-R, Barad, B.A, Fraser, J.S, DiMaio, F. | | 登録日 | 2015-02-02 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.275 Å) | | 主引用文献 | EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015
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