Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy

Summary for 3J9J

EMDB information5778
DescriptorTransient receptor potential cation channel subfamily V member 1 (1 entity in total)
Functional Keywordsalpha helical, membrane protein
Biological sourceRattus norvegicus (rat)
Cellular locationCell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein O35433
Total number of polymer chains4
Total molecular weight268939.81
Wang, R.Y.-R.,Barad, B.A.,Fraser, J.S.,DiMaio, F. (deposition date: 2015-02-02, release date: 2015-09-02, Last modification date: 2015-10-14)
Primary citation
Barad, B.A.,Echols, N.,Wang, R.Y.,Cheng, Y.,DiMaio, F.,Adams, P.D.,Fraser, J.S.
EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12:943-946, 2015
PubMed: 26280328 (PDB entries with the same primary citation)
DOI: 10.1038/nmeth.3541
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers32.2%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j9j
no rotation
Molmil generated image of 3j9j
rotated about x axis by 90°
Molmil generated image of 3j9j
rotated about y axis by 90°
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