6D1W

human PKD2 F604P mutant

Summary for 6D1W

Entry DOI	10.2210/pdb6d1w/pdb
EMDB information	7786
Descriptor	Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	ion channel, trp channel, pkd2, pc2, trpp2, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	342639.84
Authors	Zheng, W.,Yang, X.,Bulkley, D.,Chen, X.Z.,Cao, E. (deposition date: 2018-04-12, release date: 2018-06-27, Last modification date: 2020-07-29)
Primary citation	Zheng, W.,Yang, X.,Hu, R.,Cai, R.,Hofmann, L.,Wang, Z.,Hu, Q.,Liu, X.,Bulkey, D.,Yu, Y.,Tang, J.,Flockerzi, V.,Cao, Y.,Cao, E.,Chen, X.Z. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun, 9:2302-2302, 2018 Cited by PubMed: 29899465 DOI: 10.1038/s41467-018-04586-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.54 Å)

Structure validation