7TTH

Human potassium-chloride cotransporter 1 in inward-open state

Summary for 7TTH

Entry DOI	10.2210/pdb7tth/pdb
EMDB information	26115 26116
Descriptor	Solute carrier family 12 member 4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION (3 entities in total)
Functional Keywords	slc12a4, potassium-chloride transport, inward-open state, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	243316.78
Authors	Zhao, Y.X.,Cao, E.H. (deposition date: 2022-02-01, release date: 2022-06-29, Last modification date: 2022-07-13)
Primary citation	Zhao, Y.,Shen, J.,Wang, Q.,Ruiz Munevar, M.J.,Vidossich, P.,De Vivo, M.,Zhou, M.,Cao, E. Structure of the human cation-chloride cotransport KCC1 in an outward-open state. Proc.Natl.Acad.Sci.USA, 119:e2109083119-e2109083119, 2022 Cited by PubMed: 35759661 DOI: 10.1073/pnas.2109083119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.25 Å)

Structure validation