5T4D

Cryo-EM structure of Polycystic Kidney Disease protein 2 (PKD2), residues 198-703

Summary for 5T4D

Entry DOI	10.2210/pdb5t4d/pdb
EMDB information	8354 8355 8356
Descriptor	hPKD:198-703, Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	trp channel, pkd2, nanodisc, trpp, metal transport
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	240371.08
Authors	Shen, P.S.,Yang, X.,DeCaen, P.G.,Liu, X.,Bulkley, D.,Clapham, D.E.,Cao, E. (deposition date: 2016-08-29, release date: 2016-11-02, Last modification date: 2020-07-29)
Primary citation	Shen, P.S.,Yang, X.,DeCaen, P.G.,Liu, X.,Bulkley, D.,Clapham, D.E.,Cao, E. The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs. Cell, 167:763-773.e11, 2016 Cited by PubMed: 27768895 DOI: 10.1016/j.cell.2016.09.048 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation