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1HZH
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BU of 1hzh by Molmil
CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN
分子名称: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN,Uncharacterized protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Saphire, E.O, Burton, D.R, Wilson, I.A.
登録日2001-01-24
公開日2001-08-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science, 293, 2001
6AVN
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BU of 6avn by Molmil
Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A
分子名称: GLYCEROL, PENTAETHYLENE GLYCOL, PGV19 Fab heavy chain, ...
著者Sarkar, A, Wilson, I.A.
登録日2017-09-03
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6B0N
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BU of 6b0n by Molmil
Crystal structure of the cleavage-independent prefusion HIV Env glycoprotein trimer of the clade A BG505 isolate (NFL construct) in complex with Fabs PGT122 and PGV19 at 3.39 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp140, ...
著者Sarkar, A, Irimia, A, Wilson, I.A.
登録日2017-09-14
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
4O58
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BU of 4o58 by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5L
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BU of 4o5l by Molmil
Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5I
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BU of 4o5i by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6.501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5N
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BU of 4o5n by Molmil
Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
3TV3
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BU of 3tv3 by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMYLAMINE, GLYCEROL, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-19
公開日2011-10-19
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3TWC
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BU of 3twc by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9
分子名称: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-21
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
6WO3
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BU of 6wo3 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.382 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WO4
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BU of 6wo4 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WOQ
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BU of 6woq by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.667 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WO5
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BU of 6wo5 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-24
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.619 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WOS
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BU of 6wos by Molmil
Structure of broadly neutralizing antibody AR3B
分子名称: Fab AR3B heavy chain, Fab AR3B light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.645 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WOR
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BU of 6wor by Molmil
Structure of the broadly neutralizing antibody HC1AM
分子名称: Fab HC1AM heavy chain, Fab HC1AM light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
3BO8
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BU of 3bo8 by Molmil
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2007-12-17
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity
Protein Sci., 18, 2009
1ITH
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BU of 1ith by Molmil
STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION
分子名称: CYANIDE ION, HEMOGLOBIN (CYANO MET), PROTOPORPHYRIN IX CONTAINING FE
著者Hackert, M, Kolatkar, P, Ernst, S.R, Ogata, C.M, Hendrickson, W.A, Merritt, E.A, Phizackerley, R.P.
登録日1991-12-03
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure determination and refinement of homotetrameric hemoglobin from Urechis caupo at 2.5 A resolution.
Acta Crystallogr.,Sect.B, 48, 1992
2FX9
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BU of 2fx9 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein gp41
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
5CEZ
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BU of 5cez by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Fab Heavy Chain, ...
著者Wilson, I.A, Garces, F.
登録日2015-07-08
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.031 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
2FX8
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BU of 2fx8 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein (GP41)
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
5CCC
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BU of 5ccc by Molmil
wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E.
登録日2015-07-01
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
2FX7
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BU of 2fx7 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
5CEY
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BU of 5cey by Molmil
Crystal Structure of Fab 9H+3L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
分子名称: 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, ...
著者Wilson, I.A, Garces, F.
登録日2015-07-07
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.387 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CC9
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BU of 5cc9 by Molmil
L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E.
登録日2015-07-01
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
5CEX
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BU of 5cex by Molmil
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
分子名称: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
著者Garces, F, Wilson, I.A.
登録日2015-07-07
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015

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