5CEX
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Summary for 5CEX
Entry DOI | 10.2210/pdb5cex/pdb |
Related | 5CEY 5CEZ |
Descriptor | Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | hiv-1, immune system, antibody |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 99166.38 |
Authors | Garces, F.,Wilson, I.A. (deposition date: 2015-07-07, release date: 2015-12-23, Last modification date: 2023-09-27) |
Primary citation | Garces, F.,Lee, J.H.,de Val, N.,Torrents de la Pena, A.,Kong, L.,Puchades, C.,Hua, Y.,Stanfield, R.L.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43:1053-1063, 2015 Cited by PubMed: 26682982DOI: 10.1016/j.immuni.2015.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.105 Å) |
Structure validation
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