6AVN

Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A

Summary for 6AVN

Entry DOI	10.2210/pdb6avn/pdb
Descriptor	PGV19 Fab heavy chain, PGV19 Fab light chain, GLYCEROL, ... (5 entities in total)
Functional Keywords	vrc01-class lambda antibody, cd4 binding site epitope, immune system, anti-hiv neutralizing antibody
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	47072.75
Authors	Sarkar, A.,Wilson, I.A. (deposition date: 2017-09-03, release date: 2018-06-27, Last modification date: 2023-10-04)
Primary citation	Sarkar, A.,Bale, S.,Behrens, A.J.,Kumar, S.,Sharma, S.K.,de Val, N.,Pallesen, J.,Irimia, A.,Diwanji, D.C.,Stanfield, R.L.,Ward, A.B.,Crispin, M.,Wyatt, R.T.,Wilson, I.A. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nat Commun, 9:1956-1956, 2018 Cited by PubMed: 29769533 DOI: 10.1038/s41467-018-04272-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation