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5CEY

Crystal Structure of Fab 9H+3L, a putative precursor of the PGT121 family of potent HIV-1 antibodies

Summary for 5CEY
Entry DOI10.2210/pdb5cey/pdb
Related5CEX 5CEZ
DescriptorAntibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, GLYCEROL, ... (6 entities in total)
Functional Keywordshiv-1, antibody, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains4
Total formula weight98502.08
Authors
Wilson, I.A.,Garces, F. (deposition date: 2015-07-07, release date: 2015-12-23, Last modification date: 2023-09-27)
Primary citationGarces, F.,Lee, J.H.,de Val, N.,Torrents de la Pena, A.,Kong, L.,Puchades, C.,Hua, Y.,Stanfield, R.L.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A.
Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43:1053-1063, 2015
Cited by
PubMed: 26682982
DOI: 10.1016/j.immuni.2015.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.387 Å)
Structure validation

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