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8EF6
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BU of 8ef6 by Molmil
Morphine-bound mu-opioid receptor-Gi complex
分子名称: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFL
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SR17018-bound mu-opioid receptor-Gi complex
分子名称: 5,6-dichloro-1-{1-[(4-chlorophenyl)methyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFO
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BU of 8efo by Molmil
PZM21-bound mu-opioid receptor-Gi complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFB
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BU of 8efb by Molmil
Oliceridine-bound mu-opioid receptor-Gi complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFQ
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BU of 8efq by Molmil
DAMGO-bound mu-opioid receptor-Gi complex
分子名称: DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8WZ2
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BU of 8wz2 by Molmil
Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex
分子名称: G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y.
登録日2023-11-01
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor.
Cell Discov, 10, 2024
8X7A
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BU of 8x7a by Molmil
Treprostinil bound Prostacyclin Receptor G protein complex
分子名称: 2-[[(1~{R},2~{R},3~{a}~{S},9~{a}~{S})-2-oxidanyl-1-[(3~{S})-3-oxidanyloctyl]-2,3,3~{a},4,9,9~{a}-hexahydro-1~{H}-cyclopenta[g]naphthalen-5-yl]oxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C.
登録日2023-11-23
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs.
Sci Adv, 10, 2024
8X79
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BU of 8x79 by Molmil
MRE-269 bound Prostacyclin Receptor G protein complex
分子名称: 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C.
登録日2023-11-23
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs.
Sci Adv, 10, 2024
6XJX
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BU of 6xjx by Molmil
MCU holocomplex in Low-calcium blocking state
分子名称: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
著者Wang, Y, Jiang, Y.
登録日2020-06-24
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter.
Elife, 9, 2020
6XJV
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BU of 6xjv by Molmil
MCU holocomplex in High-calcium state
分子名称: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
著者Wang, Y, Jiang, Y.
登録日2020-06-24
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter.
Elife, 9, 2020
8J40
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BU of 8j40 by Molmil
Crystal Structure of CATB8 in complex with chloramphenicol
分子名称: CHLORAMPHENICOL, CatB8, GLYCEROL, ...
著者Liao, J, Kuang, L, Jiang, Y.
登録日2023-04-18
公開日2024-02-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Chloramphenicol Binding Sites of Acinetobacter baumannii Chloramphenicol Acetyltransferase CatB8.
Acs Infect Dis., 10, 2024
7RH9
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BU of 7rh9 by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in apo state
分子名称: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
著者Xue, J, Han, Y, Jiang, Y.
登録日2021-07-16
公開日2021-11-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
6CMO
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BU of 6cmo by Molmil
Rhodopsin-Gi complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ...
著者Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E.
登録日2018-03-05
公開日2018-06-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
6NBH
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BU of 6nbh by Molmil
Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein
分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y.
登録日2018-12-07
公開日2019-04-17
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
6NBF
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BU of 6nbf by Molmil
Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein
分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y.
登録日2018-12-07
公開日2019-04-17
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
6O58
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BU of 6o58 by Molmil
Human MCU-EMRE complex, dimer of channel
分子名称: CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者Wang, Y, Bai, X, Jiang, Y.
登録日2019-03-01
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019
6O5B
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BU of 6o5b by Molmil
Monomer of a cation channel
分子名称: CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者Wang, Y, Bai, X, Jiang, Y.
登録日2019-03-01
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019
6NBI
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BU of 6nbi by Molmil
Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein
分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y.
登録日2018-12-07
公開日2019-04-17
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
1AIP
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BU of 1aip by Molmil
EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
分子名称: ELONGATION FACTOR TS, ELONGATION FACTOR TU
著者Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
登録日1997-04-22
公開日1997-10-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
7N7P
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BU of 7n7p by Molmil
Cryo-EM structure of human TMEM120A
分子名称: COENZYME A, Ion channel TACAN
著者Xue, J, Han, Y, Jiang, Y.
登録日2021-06-10
公開日2021-09-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase.
Elife, 10, 2021
5BOA
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BU of 5boa by Molmil
Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb bound to the disaccharide receptor Gb2
分子名称: Translation initiation factor 2 (IF-2 GTPase), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose
著者Zhang, C, Yu, Y, Yang, M, Jiang, Y.
登録日2015-05-27
公開日2016-05-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor.
Febs Lett., 590, 2016
2AEM
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BU of 2aem by Molmil
Crystal Structures of the MthK RCK Domain
分子名称: Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
2AEJ
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BU of 2aej by Molmil
Crystal Structures of the MthK RCK Domain in no Ca2+ bound form
分子名称: Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
6OE8
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BU of 6oe8 by Molmil
The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C
分子名称: MALONATE ION, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
著者Shi, Y, Wang, T, Zhou, X.E, Liu, Q, Jiang, Y, Xu, H.E.
登録日2019-03-27
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy.
Acta Pharmacol.Sin., 40, 2019
7SQ7
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BU of 7sq7 by Molmil
Cryo-EM structure of mouse PI(3,5)P2-bound TRPML1 channel at 2.41 Angstrom resolution
分子名称: (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, ...
著者Gan, N, Han, Y, Jiang, Y.
登録日2021-11-04
公開日2022-02-02
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P 2 and rapamycin.
Proc.Natl.Acad.Sci.USA, 119, 2022

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