7CZB

The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1

Summary for 7CZB

• Entry DOI: 10.2210/pdb7czb/pdb
• EMDB information: 30508
• Descriptor: Derlin-1 (1 entity in total)
• Functional Keywords: endoplasmic reticulum associated degradation, retrotranslocation, cryo-em, transmembrane channels, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 115286.66

Authors

Rao, B.,Li, S.,Yao, D.,Wang, Q.,Xia, Y.,Jia, Y.,Shen, Y.,Cao, Y. (deposition date: 2020-09-07, release date: 2021-03-17, Last modification date: 2024-03-27)

• Primary citation: Rao, B.,Li, S.,Yao, D.,Wang, Q.,Xia, Y.,Jia, Y.,Shen, Y.,Cao, Y.; The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.; Sci Adv, 7:-, 2021; PubMed: 33658201; DOI: 10.1126/sciadv.abe8591

Experimental method

ELECTRON MICROSCOPY (3.8 Å)