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8HDO

Structure of A2BR bound to synthetic agonists BAY 60-6583

Summary for 8HDO
Entry DOI10.2210/pdb8hdo/pdb
EMDB information34676
DescriptorChimeric miniGs, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywordsgpcr, a2br, bay 60-6583, membrane protein
Biological sourceHomo sapiens (human)
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Total number of polymer chains5
Total formula weight128156.91
Authors
Cai, H.,Xu, Y.,Xu, H.E.,Jiang, Y. (deposition date: 2022-11-05, release date: 2023-01-18)
Primary citationCai, H.,Xu, Y.,Guo, S.,He, X.,Sun, J.,Li, X.,Li, C.,Yin, W.,Cheng, X.,Jiang, H.,Xu, H.E.,Xie, X.,Jiang, Y.
Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists.
Cell Discov, 8:140-140, 2022
Cited by
PubMed: 36575181
DOI: 10.1038/s41421-022-00503-1
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.87 Å)
Structure validation

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