7Y43
Crystal structure of the KAT6A WH domain and its bound double stranded DNA
Summary for 7Y43
Entry DOI | 10.2210/pdb7y43/pdb |
Descriptor | Histone acetyltransferase KAT6A, DNA (5'-D(*GP*GP*AP*GP*TP*GP*CP*GP*CP*AP*CP*TP*CP*C)-3'), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | cpg islands, winged-helix domain, acetyltransferase, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 18247.08 |
Authors | |
Primary citation | Weber, L.M.,Jia, Y.,Stielow, B.,Gisselbrecht, S.S.,Cao, Y.,Ren, Y.,Rohner, I.,King, J.,Rothman, E.,Fischer, S.,Simon, C.,Forne, I.,Nist, A.,Stiewe, T.,Bulyk, M.L.,Wang, Z.,Liefke, R. The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain. Nucleic Acids Res., 51:574-594, 2023 Cited by PubMed: 36537216DOI: 10.1093/nar/gkac1188 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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