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5ZVM
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BU of 5zvm by Molmil
Crystal Structure of the Human Coronavirus SARS HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称: Spike glycoprotein, pan-CoV inhibitory peptide EK1
著者Yan, L, Yang, B, Wilson, I.A.
登録日2018-05-11
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5ZVK
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BU of 5zvk by Molmil
Crystal Structure of the Human Coronavirus MERS HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称: Human Coronavirus MERS HR1 motif, pan-CoV inhibitory peptide EK1
著者Yan, L, Yang, B, Wilson, I.A.
登録日2018-05-11
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5ZV3
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BU of 5zv3 by Molmil
Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide
分子名称: Heavy chain of antibody CBTAU28.1, Light chain (kappa) of antibody CBTAU28.1, Peptide from Microtubule-associated protein tau
著者Zhang, H, Wilson, I.A.
登録日2018-05-09
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
6AVN
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BU of 6avn by Molmil
Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A
分子名称: GLYCEROL, PENTAETHYLENE GLYCOL, PGV19 Fab heavy chain, ...
著者Sarkar, A, Wilson, I.A.
登録日2017-09-03
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6AOP
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BU of 6aop by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-08-16
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOS
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BU of 6aos by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 3'-SLNLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-08-16
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOQ
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BU of 6aoq by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-08-16
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6B0N
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BU of 6b0n by Molmil
Crystal structure of the cleavage-independent prefusion HIV Env glycoprotein trimer of the clade A BG505 isolate (NFL construct) in complex with Fabs PGT122 and PGV19 at 3.39 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp140, ...
著者Sarkar, A, Irimia, A, Wilson, I.A.
登録日2017-09-14
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
8GF2
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BU of 8gf2 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies eCR3022.20 and CC12.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2023-03-07
公開日2023-08-23
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.
Sci.Signal., 16, 2023
2DBL
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BU of 2dbl by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
分子名称: 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
著者Arevalo, J.H, Wilson, I.A.
登録日1994-02-08
公開日1994-03-07
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
5KZC
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BU of 5kzc by Molmil
Crystal structure of an HIV-1 gp120 engineered outer domain with a Man9 glycan at position N276, in complex with broadly neutralizing antibody VRC01
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Engineered outer domain of gp120, VRC01 Fab heavy chain, ...
著者Julien, J.-P, Jardine, J.G, Diwanji, D, Schief, W.R, Wilson, I.A.
登録日2016-07-24
公開日2016-08-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
Plos Pathog., 12, 2016
6IEQ
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BU of 6ieq by Molmil
Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ...
著者Han, B.W, Wilson, I.A.
登録日2018-09-16
公開日2019-05-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
Nat Commun, 10, 2019
6KVA
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BU of 6kva by Molmil
Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope
分子名称: 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ...
著者Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
登録日2019-09-03
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
5CD3
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BU of 5cd3 by Molmil
Structure of immature VRC01-class antibody DRVIA7
分子名称: DRVIA7 Heavy Chain, DRVIA7 Light Chain
著者Kong, L, Wilson, I.A.
登録日2015-07-02
公開日2016-04-06
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
3MJ6
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BU of 3mj6 by Molmil
Crystal structure of the gammadelta T cell costimulatory receptor Junctional Adhesion Molecule-Like Protein, JAML
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, Junctional adhesion molecule-like, ...
著者Verdino, P, Wilson, I.A.
登録日2010-04-12
公開日2010-09-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.
Science, 329, 2010
3MJ7
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BU of 3mj7 by Molmil
Crystal structure of the complex of JAML and Coxsackie and Adenovirus receptor, CAR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coxsackievirus and adenovirus receptor homolog, ...
著者Verdino, P, Wilson, I.A.
登録日2010-04-12
公開日2010-09-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.
Science, 329, 2010
8V06
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BU of 8v06 by Molmil
Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ...
著者Yuan, M, Wilson, I.A.
登録日2023-11-17
公開日2024-03-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Structure, 32, 2024
8V08
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BU of 8v08 by Molmil
Crystal structure of human PLD4 co-crystallized with 5'Pi-ssDNA
分子名称: 5'-3' exonuclease PLD4, ssDNA
著者Yuan, M, Wilson, I.A.
登録日2023-11-17
公開日2024-03-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Structure, 32, 2024
8V05
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BU of 8v05 by Molmil
Crystal structure of mouse PLD3
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2023-11-17
公開日2024-03-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Structure, 32, 2024
8V07
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BU of 8v07 by Molmil
Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 30 days
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ...
著者Yuan, M, Wilson, I.A.
登録日2023-11-17
公開日2024-03-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Structure, 32, 2024
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
分子名称: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Cho, S.Y, Wilson, I.A.
登録日2023-11-22
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8VBR
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BU of 8vbr by Molmil
Structure of bovine anti-HIV Fab ElsE11
分子名称: Bovine Fab ElsE11 light chain, Bovine Fab Else11 heavy chain
著者Stanfield, R.L, Wilson, I.A.
登録日2023-12-12
公開日2024-09-04
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Plos Pathog., 20, 2024
8VBM
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BU of 8vbm by Molmil
Structure of bovine anti-HIV Fab ElsE7
分子名称: Bovine Fab ElsE7 heavy chain, Bovine Fab ElsE7 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2023-12-12
公開日2024-09-04
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Plos Pathog., 20, 2024
8VBK
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BU of 8vbk by Molmil
Structure of bovine anti-HIV Fab ElsE5
分子名称: Bovine Fab ElsE5 heavy chain, Bovine Fab ElsE5 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2023-12-12
公開日2024-09-04
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Plos Pathog., 20, 2024
8VBJ
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BU of 8vbj by Molmil
Structure of bovine anti-HIV Fab ElsE2
分子名称: Bovine Fab ElsE2 heavy chain, Bovine Fab ElsE2 light chain, POTASSIUM ION, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2023-12-12
公開日2024-09-04
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Plos Pathog., 20, 2024

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件を2024-10-02に公開中

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