8GF2
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies eCR3022.20 and CC12.3
Summary for 8GF2
Entry DOI | 10.2210/pdb8gf2/pdb |
Descriptor | Spike protein S1, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... (7 entities in total) |
Functional Keywords | antibody, sars-cov-2, sars-cov, coronavirus, spike, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 10 |
Total formula weight | 242179.53 |
Authors | |
Primary citation | Zhao, F.,Yuan, M.,Keating, C.,Shaabani, N.,Limbo, O.,Joyce, C.,Woehl, J.,Barman, S.,Burns, A.,Tran, Q.,Zhu, X.,Ricciardi, M.,Peng, L.,Smith, J.,Huang, D.,Briney, B.,Sok, D.,Nemazee, D.,Teijaro, J.R.,Wilson, I.A.,Burton, D.R.,Jardine, J.G. Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution. Sci.Signal., 16:eabk3516-eabk3516, 2023 Cited by PubMed: 37582161DOI: 10.1126/scisignal.abk3516 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.851 Å) |
Structure validation
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