6IEQ
Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22
Summary for 6IEQ
Entry DOI | 10.2210/pdb6ieq/pdb |
Related PRD ID | PRD_900118 |
Descriptor | Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, ... (14 entities in total) |
Functional Keywords | hiv-1, envelop protein, consensus sequence-based conm sosip, broadly neutralizing antibody, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 180561.42 |
Authors | Han, B.W.,Wilson, I.A. (deposition date: 2018-09-16, release date: 2019-05-22, Last modification date: 2024-03-20) |
Primary citation | Sliepen, K.,Han, B.W.,Bontjer, I.,Mooij, P.,Garces, F.,Behrens, A.J.,Rantalainen, K.,Kumar, S.,Sarkar, A.,Brouwer, P.J.M.,Hua, Y.,Tolazzi, M.,Schermer, E.,Torres, J.L.,Ozorowski, G.,van der Woude, P.,de la Pena, A.T.,van Breemen, M.J.,Camacho-Sanchez, J.M.,Burger, J.A.,Medina-Ramirez, M.,Gonzalez, N.,Alcami, J.,LaBranche, C.,Scarlatti, G.,van Gils, M.J.,Crispin, M.,Montefiori, D.C.,Ward, A.B.,Koopman, G.,Moore, J.P.,Shattock, R.J.,Bogers, W.M.,Wilson, I.A.,Sanders, R.W. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nat Commun, 10:2355-2355, 2019 Cited by PubMed: 31142746DOI: 10.1038/s41467-019-10262-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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